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What determines whether an axolotl will grow up to be male or female?

Axolotls have genetic sex-determination - a locus on an axolotl chromosome determines whether an axolotl is male or female.

In salamanders, the sex determining mechanism is referred to as ZZ/ZW and the heterogametic sex is female.

Fun Facts

Why are axolotls the most studied salamander model?

Axolotls are used because they provide a vertebrate model organism that is easy to rear and breed in the lab.

Methods to care for axolotls have been perfected over many decades and they are the only salamanders that can be bred multiple times a year.

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