Example Query:
Chemical Name = Romidepsin
SMILES = C\C=C1\NC(=O)[C@H]2CSSCC\C=C\[C@H](CC(=O)N[C@@H](C(C)C)C(=O)N2)OC(=O)[C@@H](NC1=O)C(C)C
MW = 540.69
Bioactivity = Histone deacetylase inhibitor (HDAC)
Outcome = Inhibits tail regeneration at 10 uM
Validated = Yes
Assembly V4.0: The A. mexicanum transcriptome has been deep sequenced (15,000,000 Roche 454 short sequence reads and 50K Sanger reads) and assembled. The resulting assembly V4.0 can now be BLAST searched here. Approximately 89.9% of the 14 million high quality sequences were assembled into contigs with a total length of 542 Mb.
Salamanders have served as model organisms for more than a century. A majority of the earliest embryological and morphological analyses of vertebrate development were conducted using salamander embryos. Today, salamanders continue to be the best animal models for several areas of research and a new generation of researchers are adopting salamanders – and in particular the Mexican axolotl - as their primary animal model. This webpage provides links to projects that are developing resources to enhance salamander models.
Salamander Research Network : A Slack Workspace has been setup to facilitate communication among salamander researchers. If you have not already signed up, please contact This email address is being protected from spambots. You need JavaScript enabled to view it. for an invitation to join!
